About Us

Group Companies

Astena Holdings Co., Ltd.

Address8-2, Nihombashi Honcho 4-Chome, Chuo-ku, Tokyo 103-8403 Japan
Business FunctionBusiness Management of Group companies
Official Site https://www.astena-hd.com/

Astena Holdings Companies

Fine Chemical BusinessMedical BusinessHealth & Beauty Care, Food BusinessIndustrial Chemical Business
SPERA PHARMA, Inc.
SPERA PHARMA is a pharmaceutical CMC R&D contract company spun out from the CMC Research Division of Takeda Pharmaceutical Co., Ltd. in July 2017.
We have a research team of experts experienced in CMC research for process chemistry, formulation development and analytical development in the Pharmaceutical Sciences Division of Takeda. By opening up their technology and know-how they provide services that contribute to the creation of superior pharmaceuticals and innovative medicines.
Address17-85 Jusohonmachi 2-chome, Yodogawa-ku, Osaka 532-0024, Japan
Business FunctionPharmaceuticals Contract R&D and Manufacturing
Official Site https://www.spera-pharma.co.jp/
JITSUBO Co., Ltd.
Since its establishment in 2005, JITSUBO Co., Ltd., as an R&D enterprise specializing in peptide pharmaceuticals, has engaged in the research and development of its original peptide synthesis technology, Molecular Hiving™. In addition to being a low-cost, high-quality solution, this technology features green chemistry design—a sustainability factor recently gaining momentum in Europe—and is seeing increasing adoption in the manufacturing of a broad range of peptide APIs, including everything from cosmetic products to active drug ingredients.
With years of experience and an outstanding research team, JITSUBO develops manufacturing processes for the target peptides at customers’ requests. For commercialization, JITSUBO delivers requested peptide APIs through collaborative efforts with Switzerland’s Bachem, a world-leading peptide API manufacturing CMO with whom JITSUBO has an exclusive technical cooperation partnership.
In the field of middle-molecule pharmaceuticals, which is expected to grow in the future, JITSUBO will continue to provide environmentally-friendly processes and high-quality, low-cost peptide drug substances based on Molecular Hiving™.
Address1-1-43 Suehiro-cho, Tsurumi-ku, Yokohama-shi, Kanagawa 230-0045, Japan
BusinessDevelopment of peptide synthesis Molecular Hiving™
Development and technology transfer of manufacturing process related to peptide drug substance, etc., and contract manufacturing and licensing of technology of the said drug substance
Official Site https://www.jitsubo.com/
IWAKI SEIYAKU CO., LTD.
IWAKI SEIYAKU manufactures and sells mainly ethical and OTC drugs.
Our major products, dermatological corticosteroid drugs and dermatological antifungal drugs, are available in four dosage forms: ointment, cream, lotion, and solution. We can therefore meet needs in terms of efficacy, safety, ease-to-use, and more; we have obtained the trust of many dermatologists, and we maintain a high market share.
We are confident in its ability to provide all aspects of pharmaceuticals, from design to production, based on long-term accumulated research on dermatological drugs and various dosage forms
Address8-2, Nihombashi Honcho 4-Chome, Chuo-ku, Tokyo 103-8403 Japan
Business FunctionManufacturing and Development of Drugs
Official Site http://www.iwakiseiyaku.co.jp/
IWAKI SEIYAKU SAKURA FACTORY CO., LTD.
Iwaki Seiyaku Sakura Factory has facilities capable of manufacturing pharmaceuticals in a wide range of dosage forms, including solid preparations and injections, semi-solid preparations such as ointments and creams, and liquid preparations such as sublingual fluids.
Especially for external preparations, we have facilities capable of producing 200 tons or more per year. We plan to build a system to increase the production capacity in the future through further capital investment and other measures.
In addition, we have an environment with advanced facilities that allows us to contract various types of testing, such as quality testing of materials, and sterility and animal testing of drugs, which are listed in the Japanese Pharmacopoeia.
We satisfy the requests of many customers based on the manufacturing results of various pharmaceuticals, from investigational agent manufacturing to commercial production.
Address2183-1 Teranosaku, Ota, Sakura-shi, Chiba Prefecture, Japan
Business FunctionManufacturing and Development of Drugs
Official Site http://www.iwakiseiyaku-sakura.co.jp/
IWAKI & CO., LTD.
Address8-2, Nihombashi Honcho 4-Chome, Chuo-ku, Tokyo 103-8403 Japan
Business FunctionSales of cosmetic raw materials, food ingredients and OTC drugs etc.
Official Site https://www.iwaki-kk.co.jp/iwaki.html
APROS CO., LTD.
Address16-1 Ginza 1-Chome, Chuo-ku, Tokyo 104-0061​
Business FunctionMail-order selling of cosmetics
Official Site https://www.iwaki-kk.co.jp/apros.html
MarumanH&B Co.,Ltd
Address2-12, Kandatsukasa-machi 2-chome, Chiyoda-ku, Tokyo 101-0048​
Business FunctionManufacturing and Sales of health foods, paipo, household goods, cosmetics
Official Site https://maruman.co.jp/
Meltex Inc.
Address8-2, Nihombashi Honcho 4-Chome, Chuo-ku, Tokyo 103-8403 Japan​
Business FunctionManufacturing and Sales of surface finishing chemicals
Official Site https://www.meltex.com/

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